Abnormalities of dendritic actin organization in the brindled mouse

Brain Res. 1986 Sep 24;382(2):205-12. doi: 10.1016/0006-8993(86)91331-4.

Abstract

The brindled mouse is an X-linked mutant with alterations in copper homeostasis. Ultrastructural analysis of the cerebellum and neocortex reveals several dendritic abnormalities, including the formation of Hirano bodies and other cytoskeletal alterations. Immunocytochemical evidence demonstrates that actin is a component of these microfilament lattices.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Actins / analysis*
  • Animals
  • Cerebellum / ultrastructure*
  • Cerebral Cortex / ultrastructure*
  • Crosses, Genetic
  • Dendrites / ultrastructure*
  • Female
  • Male
  • Mice
  • Mice, Neurologic Mutants / anatomy & histology*
  • Microscopy, Electron

Substances

  • Actins