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Vet Rec. 1986 Jun 7;118(23):631-2.

Eosinophilic granulomatous pneumonia in a dog.


An eosinophilic granulomatous pneumonia is described in a German shepherd dog. On thoracic radiographs and at post mortem examination disseminated pulmonary tumour-like nodules had been seen. Histologically the nodules consisted of macrophages, eosinophils, plasma cells and occasionally giant cells. In plasma cells and macrophages, large amounts of immunoglobulin G and immunoglobulin M could be demonstrated. An aetiology could not be determined, but vasculitis and cytology made an allergic reaction of type 1 and, or, type 3 most likely. The classification of pulmonary infiltration with eosinophilia (PIE-syndrome) is discussed.

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