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Environ Health Perspect. 1986 Mar;65:243-8.

Effects of phthalic acid esters (PAEs) on the neonate and aspects of teratogenic actions.

Abstract

A review of the literature reveals that several different phthalic acid esters (PAEs) are capable of causing testicular damage. Phthalate-induced zinc deficiency is consistent with germinal epithelial damage. Among experimental animals, mice perhaps show the greatest sensitivity to phthalate-induced terata, but high doses/exposure are required. Little toxicologic information is available with regard to phthalate-induced effects upon the neonate.

PMID:
3709448
PMCID:
PMC1474722
DOI:
10.1289/ehp.8665243
[Indexed for MEDLINE]
Free PMC Article

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