Abstract
Confluent cultures of rat aortic smooth muscle cells demonstrated dose-dependent potentially lethal damage repair (PLDR), with an average repair factor of 4 for a 10 Gy dose. PLDR occurred with a half-time of 2 hours and was nearly maximal by 8 h. Among other factors, PLDR may contribute to the radioresistance of large blood vessels.
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Animals
-
Aorta
-
Cell Line
-
Cell Survival / radiation effects
-
Cells, Cultured
-
Dose-Response Relationship, Radiation
-
Male
-
Muscle, Smooth, Vascular / pathology
-
Muscle, Smooth, Vascular / radiation effects*
-
Radiation Dosage
-
Radiation Injuries, Experimental / pathology*
-
Rats
-
Rats, Inbred Strains