Format

Send to

Choose Destination
Neurosci Lett. 1987 Oct 16;81(1-2):117-22.

Low-threshold calcium electrogenesis in neocortical neurons.

Author information

1
Corob Center for Medical Research, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Abstract

In slices of parietal neocortex, evidence was obtained for the existence of a low-threshold Ca2+ conductance in most neurons. This conductance became apparent when resting membrane potential was held below -60 mV by continuously injected, depolarizing current. Under these conditions, brief hyperpolarizing pulses were followed by generation of tetrodotoxin (TTX)-resistant, Mn2+-sensitive, low-threshold spikes. The results suggest that in neocortex, as in many subcortical structures, low-threshold Ca current may be responsible for burst generation in some neurons.

PMID:
3696461
DOI:
10.1016/0304-3940(87)90350-8
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center