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J Am Vet Med Assoc. 1987 Dec 1;191(11):1453-4.

Hemolytic uremic-like syndrome in two horses.

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Laboratory of Large Animal Pathology, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.


A syndrome characterized clinically by oliguria, progressive severe azotemia, and edema of the abdomen and groin was seen in 2 horses. Treatment with fluids, diuretics, and corticosteroids administered intravenously was ineffective, and the horses were euthanatized. Microscopically, there was severe necrotizing angiopathy with profuse fibrin deposition in renal glomeruli and sinusoids of peripheral lymph nodes. The signs observed in the horses resembled hemolytic-uremic syndrome in human beings.

[Indexed for MEDLINE]

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