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Arthritis Rheum. 1987 Nov;30(11):1289-92.

Development of selective IgM deficiency in systemic lupus erythematosus patients with disease of long duration.

Author information

1
Third Department of Internal Medicine, Osaka University Medical School, Japan.

Abstract

Statistical analysis of serum immunoglobulin levels in 54 systemic lupus erythematosus (SLE) patients showed a decrease in serum IgM (normal 77 +/- 26 mg/dl; P less than 0.001) that was closely related to disease duration. The longer the duration of SLE, the more striking the decrease in serum levels of IgM (r = -0.74, P less than 0.01). Selective IgM deficiency (less than 47 mg/dl) occurred in SLE patients whose disease was clinically inactive or less active.

PMID:
3689463
DOI:
10.1002/art.1780301112
[Indexed for MEDLINE]

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