Format

Send to

Choose Destination
Biochem Biophys Res Commun. 1987 Nov 30;149(1):180-6.

Identification of an arginine vasopressin-like diuretic hormone from Locusta migratoria.

Author information

1
Laboratoire de Neuroendocrinologie, UA CNRS 1138, Université de Bordeaux I, Talence, France.

Abstract

We have identified two neuropeptides (F1 and F2) from suboesophageal and thoracic ganglia of Locusta migratoria, which we isolated earlier based on their immunological similarity to arginine vasopressin. The more abundant and hydrophilic factor, F1, has sequence Cys-Leu-Ile-Thr-Asn-Cys-Pro-Arg-Gly-NH2, but its biological role is unknown. The less abundant factor, F2, is an antiparallel dimer of F1, and functions as a diuretic hormone of this species. It appears to act through the intermediacy of cyclic AMP. The properties of the native neuropeptides were identical with those of samples synthesized from appropriately protected L-amino acids.

PMID:
3689410
DOI:
10.1016/0006-291x(87)91621-4
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center