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Comp Biochem Physiol B. 1987;87(4):675-9.

Ubiquitous presence of calciferin-like and cathepsin D-like activities in the sera (vertebrates) and humoral fluids (invertebrates).

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Kitasato Institute, Tokyo, Japan.


1. Sera (or humoral fluids) from various animals (vertebrates and invertebrates) were assayed for calciferin-like and cathepsin D-like activities, indicating the ubiquitous presence of the latter and the former (with a few exceptions). Animals other than the mammals appeared to contain an organophilic calciferin-like activity in addition to a hydrophilic component (calciferin). 2. A correlation was found between the levels of calciferin and acid protease in most of the mammalian sera. An age-dependent decrease in calciferin (but not acid protease) was found in human sera. The possible presence of an acid protease-inhibitor was suggested.

[Indexed for MEDLINE]

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