Bezold-Jarisch reflex mediated syncope in pulmonary arterial hypertension: An illustrative case series

Kolade M Agboola; Gurukripa N Kowlgi; Ibolya Csecs; Hilary M DuBrock; Hector R Cajigas; Thomas G Allison

doi:10.1002/pul2.12147

Bezold-Jarisch reflex mediated syncope in pulmonary arterial hypertension: An illustrative case series

Pulm Circ. 2022 Oct 1;12(4):e12147. doi: 10.1002/pul2.12147. eCollection 2022 Oct.

Authors

Kolade M Agboola¹, Gurukripa N Kowlgi¹, Ibolya Csecs², Hilary M DuBrock³, Hector R Cajigas³, Thomas G Allison^{1

4}

Affiliations

¹ Department of Cardiovascular Medicine Mayo Clinic Rochester Minnesota USA.
² Department of Medicine Jacobi Medical Center, Albert Einstein College of Medicine New York New York USA.
³ Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine Mayo Clinic Rochester Minnesota USA.
⁴ Department of Pediatric and Adolescent Medicine, Division of Pediatric Cardiology Mayo Clinic Rochester Minnesota USA.

Abstract

We present a novel description of Bezold-Jarisch Reflex (BJR) during cardiopulmonary exercise testing (CPET) in three young female patients with Group 1 pulmonary arterial hypertension (PAH). These three cases presented within 26 months, representing only 0.8% of 11,387 tests on patients with PAH undergoing CPET during this time frame.

Keywords: Bezold–Jarisch reflex; cardiopulmonary exercise testing; pulmonary arterial hypertension; syncope.