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Am J Psychiatry. 1987 Sep;144(9):1207-9.

Augmentation of haloperidol by ascorbic acid in phencyclidine intoxication.

Abstract

The authors studied 40 white men with acute phencyclidine (PCP) intoxication. On a random basis, 10 were treated with ascorbic acid, 10 with placebo, 10 with haloperidol, and 10 with a combination of ascorbic acid and haloperidol. While haloperidol was significantly more effective than ascorbic acid, the combination was significantly more effective than either used alone. This combination may have a specific antipsychotic role in the emergency treatment of PCP psychosis.

PMID:
3631319
DOI:
10.1176/ajp.144.9.1207
[Indexed for MEDLINE]
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