SnapShot: Cancer immunoediting

Cell. 2022 Oct 13;185(21):4038-4038.e1. doi: 10.1016/j.cell.2022.09.027.

Abstract

In the tumor microenvironment, immune cells and tumor cells interact in a process called cancer immunoediting, giving rise to changes in gene expression, metabolism, mutational burden, and cellularity in the tumor. This SnapShot compares endogenous versus therapy-induced cancer immunoediting and outlines the molecular and cellular characteristics of interactions that result in complete tumor regression versus tumor escape and progression. To view this SnapShot, open or download the PDF.

MeSH terms

  • Humans
  • Mutation
  • Neoplasms / genetics
  • Neoplasms / immunology*
  • Neoplasms / therapy
  • Tumor Escape
  • Tumor Microenvironment*