Jietacins A and B, new nematocidal antibiotics from a Streptomyces sp. Taxonomy, isolation, and physico-chemical and biological properties

S Omura; K Otoguro; N Imamura; H Kuga; Y Takahashi; R Masuma; Y Tanaka; H Tanaka; X H Su; E T You

doi:10.7164/antibiotics.40.623

Jietacins A and B, new nematocidal antibiotics from a Streptomyces sp. Taxonomy, isolation, and physico-chemical and biological properties

J Antibiot (Tokyo). 1987 May;40(5):623-9. doi: 10.7164/antibiotics.40.623.

Authors

S Omura, K Otoguro, N Imamura, H Kuga, Y Takahashi, R Masuma, Y Tanaka, H Tanaka, X H Su, E T You

PMID: 3610821
DOI: 10.7164/antibiotics.40.623

Abstract

Jietacins A and B, new azoxy antibiotics, were isolated from the culture broth of a streptomycete. The antibiotics have the molecular formulae of C18H34N2O2 and C19H36N2O2, respectively. Both possess an azoxy group. They have potent activity against the pine wood nematode, Bursaphelenchus lignicolus, and are weakly active against some fungi.

MeSH terms

Animals
Antinematodal Agents / analysis*
Antinematodal Agents / toxicity
Azo Compounds / analysis*
Azo Compounds / toxicity
Carbon / metabolism
Chemical Phenomena
Chemistry, Physical
Fermentation
Mice
Spectrophotometry, Infrared
Streptomyces / analysis*
Streptomyces / classification
Streptomyces / physiology

Substances

Antinematodal Agents
Azo Compounds
jietacin A
jietacin B
Carbon