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Biochem Biophys Res Commun. 1987 Jun 30;145(3):1185-91.

Anti-lipoperoxidation action of food restriction.

Abstract

Chronic food restriction inhibited the age-related increase of malondialdehyde production and lipid hydroperoxides in liver mitochondrial and microsomal membranes of ad libitum fed Fischer 344 rats. The anti-lipoperoxidation action of food restriction could not be attributable to the changes in membrane lipid content nor vitamin E status. Restricting calories modified membrane fatty acid composition by increasing linoleic acid and decreasing docosapentaenoic acid content in both membranes. The significance of the fatty acid modification was discussed in terms of anti-lipoperoxidation and membrane fluidity.

PMID:
3606601
DOI:
10.1016/0006-291x(87)91562-2
[Indexed for MEDLINE]

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