Endolymphatic hydrops presumption tests for patients with vestibular migraine

Acta Otolaryngol. 2022 May;142(5):406-409. doi: 10.1080/00016489.2022.2080251. Epub 2022 Jun 1.

Abstract

Background: The aetiology of vestibular migraine (VM) has not yet been defined; endolymphatic hydrops (EH) has been suggested as a candidate.

Objectives: This study aimed to clarify the relationship between VM and EH using neuro-otological tests, including the EH presumption test.

Materials and methods: Fourteen patients with VM underwent caloric testing, video head impulse test (vHIT), cervical and ocular vestibular evoked myogenic potential (cVEMP and oVEMP), and EH presumption tests such as the Futaki's test and furosemide loading VEMP.

Results: Caloric testing was abnormal in two of the 14 cases (14.3%), and vHIT was abnormal in one of 12 cases (8.3%). Abnormal asymmetry ratios (ARs) of cVEMP and oVEMP were observed in two of 14 cases (14.3%) and six of 13 cases (46.2%), respectively. Futaki's test results were positive in five of 14 cases (35.7%). Furosemide loading VEMP was positive in seven of 14 cases (50.0%). Nine patients (64.3%) were positive for at least one EH presumption test.

Conclusions and significance: EH is not a rare finding in VM; however, the ratio is less than that in Meniere's disease.

Keywords: Vestibular migraine; endolymphatic hydrops; furosemide test; furosemide-loading VEMP.

MeSH terms

  • Endolymphatic Hydrops* / complications
  • Endolymphatic Hydrops* / diagnosis
  • Furosemide
  • Humans
  • Meniere Disease* / complications
  • Meniere Disease* / diagnosis
  • Migraine Disorders* / complications
  • Migraine Disorders* / diagnosis
  • Vertigo
  • Vestibular Evoked Myogenic Potentials* / physiology
  • Vestibule, Labyrinth*

Substances

  • Furosemide