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Nature. 1987 Apr 2-8;326(6112):466-70.

Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast.

Abstract

The two strands of the DNA molecule are complementary but not identical. Hence, upon semiconservative replication, different parental DNA strands are segregated to daughter cells. A molecular analysis suggests that the process of fission yeast mating-type interconversion uses asymmetry of the DNA strands to generate a regular lineage of cellular differentiation.

PMID:
3561486
DOI:
10.1038/326466a0
[Indexed for MEDLINE]

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