Biocompatible Conductive Hydrogels: Applications in the Field of Biomedicine

Int J Mol Sci. 2022 Apr 21;23(9):4578. doi: 10.3390/ijms23094578.

Abstract

The impact of COVID-19 has rendered medical technology an important factor to maintain social stability and economic increase, where biomedicine has experienced rapid development and played a crucial part in fighting off the pandemic. Conductive hydrogels (CHs) are three-dimensional (3D) structured gels with excellent electrical conductivity and biocompatibility, which are very suitable for biomedical applications. CHs can mimic innate tissue's physical, chemical, and biological properties, which allows them to provide environmental conditions and structural stability for cell growth and serve as efficient delivery substrates for bioactive molecules. The customizability of CHs also allows additional functionality to be designed for different requirements in biomedical applications. This review introduces the basic functional characteristics and materials for preparing CHs and elaborates on their synthetic techniques. The development and applications of CHs in the field of biomedicine are highlighted, including regenerative medicine, artificial organs, biosensors, drug delivery systems, and some other application scenarios. Finally, this review discusses the future applications of CHs in the field of biomedicine. In summary, the current design and development of CHs extend their prospects for functioning as an intelligent and complex system in diverse biomedical applications.

Keywords: biocompatibility; biomedical applications; conductive hydrogels; preparation materials; synthetic techniques.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemistry
  • Biocompatible Materials / therapeutic use
  • COVID-19*
  • Electric Conductivity
  • Humans
  • Hydrogels* / chemistry
  • Hydrogels* / therapeutic use
  • Tissue Engineering / methods

Substances

  • Biocompatible Materials
  • Hydrogels