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Mol Cell Biol. 1987 Feb;7(2):961-3.

Primary structure polymorphism at amino acid residue 72 of human p53.

Abstract

We analyzed p53 cDNA and genomic clones from a variety of normal and transformed cells. Sequence analysis of these clones revealed that amino acid residue 72 can be an arginine, proline, or cysteine. This single codon difference results in electrophoretically distinct forms of human p53 seen in normal and transformed cells.

PMID:
3547088
PMCID:
PMC365159
[Indexed for MEDLINE]
Free PMC Article
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