Bacteria in tumors "hit the road" together

Cell. 2022 Apr 14;185(8):1292-1294. doi: 10.1016/j.cell.2022.03.013.

Abstract

Tumors contain bacteria, but the functional significance of this tumor microbiota is not appreciated. Fu et al. show that bacteria within breast tumor cells contribute to metastasis, in part, by enhancing tumor cell survival to mechanical fluid shear stress as would be found in the circulation.

Publication types

  • Comment

MeSH terms

  • Bacteria*
  • Breast Neoplasms* / microbiology
  • Breast Neoplasms* / pathology
  • Cell Survival
  • Female
  • Humans
  • Neoplasm Metastasis*
  • Stress, Mechanical