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J Gen Microbiol. 1986 Aug;132(8):2147-53.

Transport and hydrolysis of peptides in Saccharomyces cerevisiae.

Abstract

The transport and hydrolysis of several radioactive di- and tripeptides in Saccharomyces cerevisiae was studied. A peptide-transport-deficient mutant isolated on the basis of its resistance to nikkomycin Z lost most of its capacity to take up di- and tripeptides. The transport kinetics of [14C]methionylglycine, [14C]methionylsarcosine and [3H]nikkomycin Z indicated that peptide transport is not dependent on intracellular hydrolysis. Intact cells had some peptidase activity towards methionylsarcosine but not towards nikkomycin Z. The relationship between this activity and peptide transport is discussed.

PMID:
3540196
DOI:
10.1099/00221287-132-8-2147
[Indexed for MEDLINE]

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