How I do it: endonasal transcribriform approach for resection of esthesioneuroblastoma

Acta Neurochir (Wien). 2022 Jul;164(7):1949-1952. doi: 10.1007/s00701-022-05178-x. Epub 2022 Mar 16.

Abstract

Background: Olfactory neuroblastoma, also known as esthesioneuroblastoma, accounts for only 3-6% of sinonasal malignancies but confers a 40% 5-year overall survival.

Method: The authors describe techniques for the endonasal, minimally invasive resection of an esthesioneuroblastoma in a 69-year-old man who presented with headaches and anosmia and describe surgical nuances and their effect on adjuvant therapy planning.

Conclusion: This approach, along with microsurgical techniques, helped increase tumor visualization, improved marginal resection, and reduced surgical risk, which may improve patient outcomes. Multilayered reconstruction with a synthetic dural substitute and creation of a nasoseptal flap were performed to reduce postoperative cerebrospinal fluid leak.

Keywords: Endoscopic; Esthesioneuroblastoma; Minimally invasive; Olfactory neuroblastoma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Endoscopy / methods
  • Esthesioneuroblastoma, Olfactory* / surgery
  • Humans
  • Male
  • Nasal Cavity / surgery
  • Nose Neoplasms* / surgery
  • Plastic Surgery Procedures* / methods
  • Retrospective Studies
  • Skull Base / surgery
  • Surgical Flaps / surgery