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Acta Neurol Scand. 1978 Mar;57(3):232-8.

Baclofen trial in six myotonic dystrophy patients.

Abstract

Six young adult patients with grade I myotonic dystrophy and a complaint of daytime somnolence underwent 36-hour polygraphic monitoring, dynamometric and electromyographic studies before and under baclofen (60 mg/daily). Patients with the most severe daytime sleepiness had pathologic Sleep Apnea Indexes. After 6 weeks' ingestion of baclofen, no subjective or objective effect on patient symptomatology was found.

PMID:
352086
[PubMed - indexed for MEDLINE]
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