Annular bullous diseases

Clin Dermatol. 2022 Sep-Oct;40(5):516-528. doi: 10.1016/j.clindermatol.2021.12.012. Epub 2022 Jan 1.

Abstract

Annular bullous dermatoses represent an etiologically diverse group of cutaneous phenomena that present with a figurate morphology in association with vesicles and bullae. This group of diverse conditions consists of bullous pemphigoid; pemphigoid gestationis; epidermolysis bullosa simplex, Dowling-Meara type; linear immunoglobulin A bullous dermatosis; chronic bullous disease of childhood; anti-p200 pemphigoid; subcorneal pustular dermatosis; and immunoglobulin A pemphigus. Astute examination of clinical, histopathologic, and serologic features is crucial in distinguishing these bullous dermatoses. We review the clinical presentation, pathophysiology, histopathology, and treatments for each bullous annular disease to aid physicians in their recognition, diagnosis, and management.

Publication types

  • Review

MeSH terms

  • Autoimmune Diseases*
  • Blister
  • Humans
  • Immunoglobulin A
  • Linear IgA Bullous Dermatosis*
  • Pemphigoid, Bullous* / diagnosis
  • Pemphigus*
  • Skin Diseases, Vesiculobullous* / diagnosis
  • Skin Diseases, Vesiculobullous* / pathology

Substances

  • Immunoglobulin A