In Vivo Reflectance Confocal Microscopy of Adnexal Tumors: Evaluation of Trichoepithelioma, Sebaceoma, and Fibrofolliculoma

Am J Dermatopathol. 2022 Mar 1;44(3):190-195. doi: 10.1097/DAD.0000000000002064.

Abstract

Cutaneous adnexal tumors are benign and malignant neoplasms that undergo morphological differentiation into cutaneous adnexa, comprising pilosebaceous, eccrine, or apocrine units. Reflectance confocal microscopy is a noninvasive diagnostic method that enables in vivo visualization of tissues at a similar resolution as conventional histopathology. The use of this method in skin imaging over the past several years has improved dermatological diagnoses, potentiating its wide application, especially for benign and malignant skin tumors. We describe the use of reflectance confocal microscopy in cases of trichoepithelioma, sebaceoma, and fibrofolliculoma and correlate the resulting clinical, histopathological, and confocal microscopy images.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muir-Torre Syndrome / diagnosis
  • Muir-Torre Syndrome / pathology*
  • Neoplasms, Adnexal and Skin Appendage / diagnosis
  • Neoplasms, Adnexal and Skin Appendage / pathology*
  • Neoplastic Syndromes, Hereditary / diagnosis
  • Neoplastic Syndromes, Hereditary / pathology*
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / pathology*

Supplementary concepts

  • Familial cylindromatosis
  • Trichoepitheliomas, Multiple Desmoplastic