Primary localized amyloidosis of the ureter with osseous metaplasia presenting as a suspicious ureteral mass

Nada Shaker; Zofia Tynski; Madeline Hudlak; Roy R Brown; Shadi Qasem; Anil Parwani

doi:10.1016/j.eucr.2021.101967

Primary localized amyloidosis of the ureter with osseous metaplasia presenting as a suspicious ureteral mass

Urol Case Rep. 2021 Dec 6:41:101967. doi: 10.1016/j.eucr.2021.101967. eCollection 2022 Mar.

Authors

Nada Shaker¹, Zofia Tynski², Madeline Hudlak³, Roy R Brown⁴, Shadi Qasem⁵, Anil Parwani⁶

Affiliations

¹ PGY-1, Department of Pathology, The Ohio State University Wexner Medical Center, E411 Doan Hall, 410 W. 10th Ave, Columbus, OH, 43210, USA.
² Department of Pathology, Fairfield Medical Center, Lancaster, OH, USA.
³ Internal Medicine Resident PGY-2, Fairfield Medical Center, Lancaster, OH, USA.
⁴ Fairfield Medical Center, Lancaster, OH, USA.
⁵ Surgical Pathology, Department of Pathology, The University of Kentucky, Lexington, KY, USA.
⁶ Anatomic Pathology, Department of Pathology, The Ohio State University Wexner Medical Center, E411 Doan Hall, 410 W. 10th Ave, Columbus, OH, 43210, USA.

Abstract

Primary amyloidosis of the ureter is a rare disease that is difficult to distinguish from urothelial carcinoma. Only 50 cases of primary ureter amyloidosis have been reported since it was first described in 1937. Of these, only five cases of ureter amyloidosis with osseous metaplasia were reported. In this study, we report the clinical presentation of ureter primary amyloidosis that presented as a mass with osseous metaplasia. The aim of this study is to provide clinicians with knowledge about the clinical/radiologic manifestation that raise the suspicion of amyloidosis, bearing in mind the importance of differentiating it from other "malignant" processes.

Keywords: Oncology; Osseous metaplasia; Primary amyloidosis; Ureter amyloidosis.

Publication types

Case Reports