[Comparative evaluation of the respiratory function and the acid-base equilibrium in patients with chronic bronchopulmonary disease after intravenous administration of 5 beta receptor agonists]

Minerva Med. 1979 Jan 7;70(1):51-7.
[Article in Italian]

Abstract

The Authors studied lung mechanics, acid-base balance parameters, arterial blood pressure and pulse rate in five different groups of chronic obstructive lung disease patients, undergoing e.v. different bronchodilators. The drug were: 1. group: 500 gamma of orciprenalina; 2. group: 500 gamma of idrossi-fenil-orciprenalina; 3. group: 200 gamma of salbutamolo; 4. group: 100 gamma of trimetochinolo; 5. group: 500 gamma of terbutalina. The comparative analysis of bronchodilators, their cardiovascular effects and on acid-base balance indicate that mainly salbutamol and trimetochinol have negligeable adverse effects.

MeSH terms

  • Acid-Base Equilibrium / drug effects*
  • Adrenergic beta-Agonists / therapeutic use*
  • Albuterol / therapeutic use
  • Humans
  • Metaproterenol / analogs & derivatives
  • Metaproterenol / therapeutic use
  • Respiratory Distress Syndrome / drug therapy
  • Respiratory Distress Syndrome / physiopathology*
  • Respiratory Function Tests
  • Terbutaline / therapeutic use
  • Tretoquinol / therapeutic use

Substances

  • Adrenergic beta-Agonists
  • Metaproterenol
  • Tretoquinol
  • Terbutaline
  • Albuterol