COVID-19 vaccination and cancer immunotherapy: should they stick together?

Br J Cancer. 2022 Jan;126(1):1-3. doi: 10.1038/s41416-021-01618-0. Epub 2021 Nov 19.

Abstract

The combination of COVID-19 vaccination with immunotherapy by checkpoint inhibitors in cancer patients could intensify immunological stimulation with potential reciprocal benefits. Here, we examine more closely the possible adverse events that can arise in each treatment modality. Our conclusion is that caution should be exercised when combining both treatments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • BNT162 Vaccine / administration & dosage
  • BNT162 Vaccine / adverse effects*
  • BNT162 Vaccine / immunology
  • COVID-19 / immunology
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / administration & dosage
  • COVID-19 Vaccines / adverse effects
  • COVID-19 Vaccines / immunology
  • Combined Modality Therapy / adverse effects
  • Cytokine Release Syndrome / etiology
  • Drug Interactions
  • Humans
  • Immune Checkpoint Inhibitors / administration & dosage
  • Immune Checkpoint Inhibitors / adverse effects*
  • Immunotherapy / adverse effects*
  • Immunotherapy / methods
  • Neoplasms / immunology
  • Neoplasms / therapy*

Substances

  • COVID-19 Vaccines
  • Immune Checkpoint Inhibitors
  • BNT162 Vaccine