Late Pre-term Infants with Severe Bronchiolitis and Risk of Asthma by Age 5 Years

Jonathan M Mansbach; Ying Shelly Qi; Janice A Espinola; Kohei Hasegawa; Henry T Puls; Ashley F Sullivan; Carlos A Camargo Jr

doi:10.1016/j.jpeds.2021.09.037

Late Pre-term Infants with Severe Bronchiolitis and Risk of Asthma by Age 5 Years

J Pediatr. 2022 Feb:241:247-250.e1. doi: 10.1016/j.jpeds.2021.09.037. Epub 2021 Sep 29.

Authors

Jonathan M Mansbach¹, Ying Shelly Qi², Janice A Espinola², Kohei Hasegawa², Henry T Puls³, Ashley F Sullivan², Carlos A Camargo Jr²

Affiliations

¹ Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA. Electronic address: jonathan.mansbach@childrens.harvard.edu.
² Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
³ Department of Pediatrics, Children's Mercy Kansas City, University of Missouri-Kansas City School of Medicine, Kansas City, MO.

Abstract

In a prospective, multicenter cohort of infants hospitalized with bronchiolitis, we found infants born late pre-term (ie, gestational age of 34-36.9 weeks) had 35% higher odds of having asthma by age 5 years compared with infants born at full-term.

Keywords: hospitalization; intensive care; pulmonary function; wheezing.

Publication types

Multicenter Study
Research Support, N.I.H., Extramural

MeSH terms

Asthma / etiology*
Bronchiolitis / physiopathology*
Child, Preschool
Female
Gestational Age
Humans
Infant
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / etiology
Infant, Premature, Diseases / physiopathology*
Male
Patient Acuity
Prospective Studies
Risk Factors

Abstract

Publication types

MeSH terms

Grants and funding