Pain or gain?

Elife. 2021 Sep 29:10:e73378. doi: 10.7554/eLife.73378.

Abstract

The 3D structures of a membrane protein called TMEM120A suggest that it may act as an enzyme in fat metabolism rather than as an ion channel that senses mechanical pain.

Keywords: TMEM120; coenzyme A; cryo-EM structure; human; ion channel; mechanosensation; membrane protein; molecular biophysics; mouse; neuroscience; structural biology.

Publication types

  • Comment

MeSH terms

  • Cryoelectron Microscopy
  • Humans
  • Membrane Proteins*
  • Pain*

Substances

  • Membrane Proteins