Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g

Ranjit Philip; Jeffrey Towbin; Neil Tailor; Vijaya Joshi; Jason N Johnson; Ronak Naik; B Rush Waller 3rd; Shyam Sathanandam

doi:10.3390/children8090826

Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g

Children (Basel). 2021 Sep 21;8(9):826. doi: 10.3390/children8090826.

Authors

Ranjit Philip^{1

2}, Jeffrey Towbin^{1

2}, Neil Tailor^{1

2}, Vijaya Joshi^{1

2}, Jason N Johnson^{1

2}, Ronak Naik^{1

2}, B Rush Waller 3rd^{1

2}, Shyam Sathanandam^{1

2}

Affiliations

¹ Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
² The Heart Institute, Le Bonheur Children's Hospital, Memphis, TN 38103, USA.

Abstract

The transcatheter closure of patent ductus arteriosus (TCPC) has been demonstrated to be feasible even in infants weighing ≤1000 g. However, other percutaneous cardiac interventions (PCI) for such small infants born with congenital heart defects (CHD) or acquired heart defects (AHD) have not been well described. The purpose of this study was to describe the feasibility and safety of PCI in infants ≤1000 g. A retrospective review was conducted between June 2015 and May 2021, looking at 148 consecutive PCIs performed on infants weighing ≤1000 g at the time of the procedure. The procedural success rate was 100%. The major adverse event (AE) rate for TCPC was 3%, while there were no major AEs for other PCI. It is feasible to perform PCIs in infants weighing ≤1000 g with CHD and AHD using currently available technologies.

Keywords: PDA closure; acquired heart defects; cardiac catheterization; coarctation stenting; congenital heart defects; low birthweight; prematurity; pulmonary valvuloplasty.