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J Neuroimmunol. 1986 Mar;11(1):53-6.

Infection of mice with lactic dehydrogenase virus prevents development of experimental allergic encephalomyelitis.


A significant reduction in the incidence of experimental allergic encephalomyelitis (EAE) in SJL/J mice was observed when mice were infected with lactic dehydrogenase virus (LDV) 14 days before, on day 0, or 3 days after immunization with spinal cord homogenate. These results are discussed in terms of the selective infection by LDV of I-region-associated antigen- (Ia) positive macrophages.

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