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Effect of activated charcoal on endotoxin adsorption. Part I. An in vitro study.

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Artificial Liver Research Laboratory, Chongqing University of Medical Sciences, Sichuan, China.


An in vitro study by using cross-linked agarose coated activated charcoal (CAAC-II) as adsorbent was conducted. Endotoxin was quantitatively measured by chromogenic method of limulus lysate test. Results of the study demonstrated that endotoxin was fairly efficiently removed by CAAC-II. It may therefore be possible for effective adsorption of endotoxin in vivo studies and warrant further experimental study for CAAC-II hemoperfusion in clinical endotoxemia.

[Indexed for MEDLINE]

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