A simple model for control of COVID-19 infections on an urban campus

Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105292118. doi: 10.1073/pnas.2105292118.

Abstract

A customized susceptible, exposed, infected, and recovered compartmental model is presented for describing the control of asymptomatic spread of COVID-19 infections on a residential, urban college campus embedded in a large urban community by using public health protocols, founded on surveillance testing, contact tracing, isolation, and quarantine. Analysis in the limit of low infection rates-a necessary condition for successful operation of the campus-yields expressions for controlling the infection and understanding the dynamics of infection spread. The number of expected cases on campus is proportional to the exogenous infection rate in the community and is decreased by more frequent testing and effective contact tracing. Simple expressions are presented for the dynamics of superspreader events and the impact of partial vaccination. The model results compare well with residential data from Boston University's undergraduate population for fall 2020.

Keywords: COVID-19; infection modeling; surveillance testing.

MeSH terms

  • Boston
  • COVID-19 / epidemiology
  • COVID-19 / prevention & control*
  • COVID-19 / transmission
  • Contact Tracing / methods
  • Humans
  • Infection Control / methods*
  • Models, Biological
  • Public Health
  • Quarantine
  • SARS-CoV-2 / isolation & purification*
  • Students
  • Universities*
  • Urban Population