BET inhibitors enhance embryonic and fetal globin expression in erythroleukemia cell lines

Haematologica. 2021 Dec 1;106(12):3223-3227. doi: 10.3324/haematol.2021.278791.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line
  • Fetus
  • Gene Expression Regulation
  • Globins* / genetics
  • Humans
  • Leukemia, Erythroblastic, Acute* / drug therapy
  • Leukemia, Erythroblastic, Acute* / genetics
  • Leukemia, Erythroblastic, Acute* / metabolism

Substances

  • Globins

Grants and funding

Funding: this work was supported by a grant by the Edwards P. Evans Foundation/EvansMDS to AW and LAG. Funding for JZC was supported by the University of Chicago Biological Sciences Division Dean’s Office, the University of Chicago Comprehensive Cancer Center Women’s Board, and the Goldblatt Scholarship.