Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Med. 1988 Feb;84(2):215-7.

Central nervous system histoplasmosis. An unappreciated complication of the acquired immunodeficiency syndrome.

Author information

1
Department of Medical Specialties, University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston 77030.

Abstract

Involvement of the central nervous system (CNS) by Histoplasma capsulatum is a rare event. It is usually not included in the differential diagnosis of CNS lesions in patients with acquired immunodeficiency syndrome (AIDS). Herein are described four patients with AIDS and progressive disseminated histoplasmosis who had CNS involvement. Histoplasmosis in the CNS may produce meningitis, single or multiple brain abscesses, and may present with either a clinical picture of obtundation or a deteriorating space-occupying CNS lesion. Three of the four patients were treated with amphotericin B and had initial clinical response, but ultimately, all experienced a relapse and died from their infection.

PMID:
3407651
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center