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J Nerv Ment Dis. 1988 Aug;176(8):475-9.

An elaborate description of the symptomatology of patients with Research Diagnostic Criteria endogenous depression.

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Psychiatric Clinic AZUA, Amsterdam, The Netherlands.


The symptomatology of 46 patients with an established diagnosis of Research Diagnostic Criteria (RDC) endogenous depression was described by means of a 46-item symptom checklist, the Amsterdam Depression List (ADL), second version. Thirty symptoms were identified as common or very common symptoms of RDC endogenous depression. Among these common or very common symptoms only eight were RDC endogenous symptoms, and two of these were obligatory inclusion criteria. The ADL revealed 22 nonendogenous symptoms (according to RDC) to be common or very common symptoms of patients with RDC endogenous depression. The core symptoms, depressed mood and loss of pleasure, appeared to be weakly correlated with each other. Of the remaining 28 common or very common symptoms, 12 correlated significantly with at least one of the core symptoms and 16 did not. Dexamethasone suppression test suppressors and nonsuppressors did not differ, either in symptomatology or in severity of the syndrome.

[Indexed for MEDLINE]

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