Myasthenia gravis and prostatic neoplasia: a rare association

BMJ Case Rep. 2021 May 21;14(5):e242416. doi: 10.1136/bcr-2021-242416.

Abstract

An 88-year-old male patient presented with left ptosis, diplopia, muscle weakness of the lower limbs, dysphagia for solids, dysphonia and constipation. On investigation, he was found to have myasthenia gravis (MG). Further evaluation for the possible cause of MG, with CT scan, revealed that the patient had concomitant prostatic cancer. The patient was given steroids and pyridostigmine, with consequent resolution of his neurological symptoms. This is a rare case of MG associated with prostatic cancer.

Keywords: neurology; neuromuscular disease; prostate cancer.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Blepharoptosis*
  • Diplopia
  • Humans
  • Male
  • Myasthenia Gravis* / complications
  • Myasthenia Gravis* / diagnosis
  • Myasthenia Gravis* / drug therapy
  • Prostatic Neoplasms* / complications
  • Prostatic Neoplasms* / drug therapy
  • Pyridostigmine Bromide / therapeutic use

Substances

  • Pyridostigmine Bromide