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Somat Cell Mol Genet. 1988 Jul;14(4):407-10.

Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22.

Author information

1
Eleanor Roosevelt Institute for Cancer Research, Denver, Colorado 80206.

Abstract

Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.

PMID:
3399965
DOI:
10.1007/bf01534649
[Indexed for MEDLINE]

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