In this study techniques were employed to induce exercising subjects to focus attention on themselves or on an external event. A total of 20 adult subjects (10 men and 10 women) were familiarized with a treadmill exercise protocol and then on two subsequent occasions performed submaximal exercise followed by a run to exhaustion under attentional conditions of self-focus (watching themselves in a mirror while listening to their breathing) and external focus (watching and listening to a movie). The order of focus conditions was counterbalanced among subjects. Analysis of postexperimental responses from subjects indicated that the procedures used to induce each type of attentional focus were successful. However, physiological and psychological responses in the two focus conditions were not always uniform for men and women, particularly during light work when men tended to have higher heart rates and significantly lower Rated Perceived Exertion while women had lower heart rates and higher Rated Perceived Exertion under self-focused conditions than under externally focused conditions. Possible explanations for the incongruence of physiological and psychological responses of men and women to the two types of attentional focus are discussed.