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Fortschr Med. 1979 Feb 22;97(8):359-61.

[Testing antacid with intragastric Ph measurements and gastroscopy].

[Article in German]

Abstract

In connection with the testing of an antacid in form of a suspension, pH-measurement and gastroscopy are carried out in the same 11 patients. Essential criteria of the efficacy of an antacid are its buffering capacity and its retention in the stomach as a mechanical protective for the gastric mucosa. The Talcid suspension tested in this way showed a good period of stay in the stomach, often exceeding the period of acid-binding capacity. Compared with bicarbonate, its buffering period is about twice as long above pH 4.5 and about 2 1/2 times as long at lower pH's.

PMID:
33887
[Indexed for MEDLINE]

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