A Retrospective Analysis of Perioperative Chemotherapy and Coronavirus Disease in Patients With Breast Cancer

Anticancer Res. 2021 Apr;41(4):2193-2195. doi: 10.21873/anticanres.14994.

Abstract

Background/aim: Since January 2020, coronavirus disease (COVID-19) cases have been confirmed in Japan, and the number of patients with COVID-19 has been increasing. Two emergency declarations have been made previously and one is currently in effect. Based on our experience of a situation that could affect cancer treatment, this study retrospectively examined the correlation between perioperative anticancer therapy and COVID-19 incidence in patients with breast cancer.

Patients and methods: Patients who underwent perioperative anticancer therapy for breast cancer at our hospital from February 2020 to February 2021 were included in this study. The presence or absence of COVID-19, timing of anticancer drug initiation, and clinical data were collected.

Results: No cases of COVID-19 were diagnosed in patients receiving perioperative anticancer therapy at our hospital.

Conclusion: Regimen modification, active use of supportive care, and patient lifestyle were factors reducing the incidence of COVID-19.

Keywords: Covid-19; breast cancer; chemotherapy.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Breast Neoplasms* / drug therapy
  • Breast Neoplasms* / epidemiology
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / surgery
  • COVID-19 / epidemiology*
  • Chemotherapy, Adjuvant / statistics & numerical data
  • Combined Modality Therapy
  • Female
  • Humans
  • Immunocompromised Host
  • Incidence
  • Japan / epidemiology
  • Middle Aged
  • Neoadjuvant Therapy / statistics & numerical data
  • Perioperative Care / adverse effects
  • Perioperative Care / methods*
  • Perioperative Care / statistics & numerical data
  • Retrospective Studies
  • Risk Factors
  • SARS-CoV-2 / physiology