Abstract
Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The test provides a scalable route to sensitive, specific, rapid and low cost mass testing.
MeSH terms
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Angiotensin-Converting Enzyme 2 / chemistry*
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Angiotensin-Converting Enzyme 2 / metabolism
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Biosensing Techniques / instrumentation
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Biosensing Techniques / methods*
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COVID-19 / diagnosis
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COVID-19 Testing / instrumentation
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COVID-19 Testing / methods
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Electrochemical Techniques / instrumentation
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Electrochemical Techniques / methods*
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Electrodes
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Enzymes, Immobilized / chemistry*
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Enzymes, Immobilized / metabolism
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Fluorocarbons / chemistry
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Gold / chemistry
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Humans
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Limit of Detection
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SARS-CoV-2 / isolation & purification*
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SARS-CoV-2 / metabolism
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Spike Glycoprotein, Coronavirus / metabolism
Substances
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Enzymes, Immobilized
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Fluorocarbons
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Spike Glycoprotein, Coronavirus
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spike protein, SARS-CoV-2
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Gold
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Angiotensin-Converting Enzyme 2