Unsuspected Bladder Diverticulum Resulted in False-Positive 68Ga-DOTATATE Uptake

Clin Nucl Med. 2021 Jun 1;46(6):477-479. doi: 10.1097/RLU.0000000000003571.

Abstract

A 67-year-old woman with medullary thyroid cancer was referred for a 68Ga-DOTATATE PET/CT scan for staging. The images showed abnormal activity in the left thyroid gland and the left cervical lymph nodes. Surprisingly, increased activity was also noted in the posterolateral aspect of the urinary bladder without corresponding anatomical abnormality. This activity disappeared after urination, suggesting false-positive uptake due to bladder diverticulum.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biological Transport
  • Diverticulum / diagnostic imaging*
  • Diverticulum / metabolism*
  • False Positive Reactions
  • Female
  • Humans
  • Incidental Findings
  • Organometallic Compounds / metabolism*
  • Positron Emission Tomography Computed Tomography
  • Urinary Bladder / abnormalities*
  • Urinary Bladder / diagnostic imaging
  • Urinary Bladder / metabolism

Substances

  • Organometallic Compounds
  • gallium Ga 68 dotatate

Supplementary concepts

  • Bladder Diverticulum