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Biull Eksp Biol Med. 1988 Apr;105(4):445-7.

[Morphofunctional changes in the pancreas in response to dalargin under normal conditions and in experimental pancreatitis].

[Article in Russian]


The influence of dalargin on pancreatic secretion stimulated by different agents has been studied in experiments on dogs. Intravenous infusion of dalargin (50 micrograms/kg/hour) induced intensive inhibition of both secretion volume and protease content. The data have been obtained on a positive influence of dalargin on acute experimental pancreatitis in rats. A reduction in synthetic processes in acinar cells, reestablishment of microcirculation in the affected zones and the absence of disturbances in the marginal zones of the pancreas have been observed.

[Indexed for MEDLINE]

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