Cutaneous Metastasis From Parotid Tumors: A Report of 2 Cases and Literature Review

Am J Dermatopathol. 2021 Jul 1;43(7):514-520. doi: 10.1097/DAD.0000000000001893.

Abstract

Cutaneous metastases from parotid tumors are uncommon and imply a poor prognosis. In this article, we report 2 new cutaneous metastasis cases from 2 different parotid malignancies and 42 additional cases from a literature review. Clinical manifestations, localization, and outcomes of skin metastasis from parotid tumors are described. Although infrequent, parotid neoplasms may develop skin metastasis many years after the initial diagnosis, mostly in the head and neck region. Therefore, long-term follow-up and periodic skin examination of these patients is mandatory. Dermatologists and surgeons must have a high index of suspicion when evaluating any skin lesion arising on these patients because cutaneous metastasis from parotid neoplasms generally implies a poor prognosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenoma, Pleomorphic / pathology*
  • Adenoma, Pleomorphic / therapy
  • Aged
  • Carcinoma, Acinar Cell / secondary*
  • Carcinoma, Acinar Cell / therapy
  • Female
  • Humans
  • Middle Aged
  • Parotid Neoplasms / pathology*
  • Parotid Neoplasms / therapy
  • Skin Neoplasms / secondary*
  • Skin Neoplasms / therapy
  • Time Factors
  • Treatment Outcome