COVID-19-Related Potential Multisystem Inflammatory Syndrome in Childhood in a Neonate Presenting as Persistent Pulmonary Hypertension of the Newborn

Rekha Khaund Borkotoky; Puja Banerjee Barua; Siba Prosad Paul; Paul Anthony Heaton

doi:10.1097/INF.0000000000003054

COVID-19-Related Potential Multisystem Inflammatory Syndrome in Childhood in a Neonate Presenting as Persistent Pulmonary Hypertension of the Newborn

Pediatr Infect Dis J. 2021 Apr 1;40(4):e162-e164. doi: 10.1097/INF.0000000000003054.

Authors

Rekha Khaund Borkotoky¹, Puja Banerjee Barua¹, Siba Prosad Paul^{1

2}, Paul Anthony Heaton²

Affiliations

¹ From the Department of Pediatrics, Apollo Hospitals (Unit: International Hospital), Guwahati, Assam, India.
² Department of Paediatrics, Yeovil District Hospital, Yeovil, United Kingdom.

PMID: 33464010
DOI: 10.1097/INF.0000000000003054

Abstract

A term infant with persistent pulmonary hypertension of newborn developed clinical and laboratory features of multisystem inflammatory syndrome in childhood (MIS-C) between days 12 and 14. Mother and baby were anti-SARS-Coronavirus-2 (SARS-CoV-2) IgG positive and anti-SARS-CoV-2 IgM negative on day 18, with negative COVID-19 PCR on repeated testing; possible first documentation of neonatal MIS-C following passive transfer of maternal antibodies.

MeSH terms

Antibodies, Viral / blood
Antibodies, Viral / immunology
Biomarkers
COVID-19 / complications
COVID-19 / diagnosis*
Diagnosis, Differential
Humans
Hypertension, Pulmonary / diagnosis*
Hypertension, Pulmonary / etiology
Infant, Newborn
Male
Symptom Assessment
Systemic Inflammatory Response Syndrome / complications
Systemic Inflammatory Response Syndrome / diagnosis*
Tomography, X-Ray Computed

Substances

Antibodies, Viral
Biomarkers

Supplementary concepts

pediatric multisystem inflammatory disease, COVID-19 related