Loss of PALB2 predicts poor prognosis in acute myeloid leukemia and suggests novel therapeutic strategies targeting the DNA repair pathway

Blood Cancer J. 2021 Jan 7;11(1):7. doi: 10.1038/s41408-020-00396-x.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • DNA Repair*
  • Fanconi Anemia Complementation Group N Protein / genetics*
  • Female
  • Gene Deletion
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Polymorphism, Single Nucleotide
  • Prognosis
  • Young Adult

Substances

  • Fanconi Anemia Complementation Group N Protein
  • PALB2 protein, human