Early Postoperative Thrombosis of Transcatheter Aortic Valve-in-Valve Prosthesis

Alessandra Francica; Mikhail Dodonov; Filippo Tonelli; Gaetano Paolino; Gabriele Pesarini; Flavio Ribichini; Giuseppe Faggian; Francesco Onorati

doi:10.1016/j.athoracsur.2020.10.062

Early Postoperative Thrombosis of Transcatheter Aortic Valve-in-Valve Prosthesis

Ann Thorac Surg. 2021 Jul;112(1):e21-e22. doi: 10.1016/j.athoracsur.2020.10.062. Epub 2021 Jan 4.

Authors

Alessandra Francica¹, Mikhail Dodonov², Filippo Tonelli², Gaetano Paolino³, Gabriele Pesarini⁴, Flavio Ribichini⁴, Giuseppe Faggian², Francesco Onorati²

Affiliations

¹ Division of Cardiac Surgery, University of Verona Medical School, Verona, Italy. Electronic address: alessandrafrancica@yahoo.it.
² Division of Cardiac Surgery, University of Verona Medical School, Verona, Italy.
³ Division of Pathological Anatomy, University of Verona Medical School, Verona, Italy.
⁴ Division of Cardiology, University of Verona Medical School, Verona, Italy.

PMID: 33412136
DOI: 10.1016/j.athoracsur.2020.10.062

Abstract

Valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) has been popularized as an attractive alternative to redo surgical aortic valve replacement for bioprosthetic valve dysfunction. Acute valve thrombosis has been occasionally described after ViV-TAVR. Lack of anticoagulant therapy has been always considered a crucial risk factor. This report describes a rare case of early postoperative fatal ViV-TAVR thrombosis despite adequate anticoagulation in addition to dual antiplatelet therapy.

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Aortic Valve / pathology*
Aortic Valve / surgery
Aortic Valve Stenosis / diagnosis
Aortic Valve Stenosis / surgery*
Bioprosthesis / adverse effects*
Fatal Outcome
Follow-Up Studies
Heart Valve Prosthesis / adverse effects*
Humans
Male
Prosthesis Design
Prosthesis Failure
Risk Factors
Thrombosis / diagnosis
Thrombosis / etiology*
Time Factors
Transcatheter Aortic Valve Replacement / adverse effects*