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Arch Ophthalmol. 1988 Jan;106(1):68-9.

Corneal toxicity of propamidine.

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Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, TN 37232.

Erratum in

  • Arch Ophthalmol 1988 Nov;106(11):1504.


Two patients with Acanthamoeba keratitis developed a corneal abnormality following prolonged treatment with topical 0.1% [corrected] propamidine isethionate. In both instances, withdrawal of drug therapy resulted in a gradual clearing of the keratopathy, with no permanent sequelae. The changes we observed may be confused with those of active Acanthamoeba infection.

[Indexed for MEDLINE]

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