Format

Send to

Choose Destination
J Med Vet Mycol. 1987 Dec;25(6):415-8.

Extracellular iron chelation in Cryptococcus neoformans.

Author information

1
Research Service, McGuire Veterans Administration Medical Center, Richmond, Virginia 23249.

Abstract

Low-iron minimal medium supported growth of Cryptococcus neoformans but spent medium contained no hydroxamates, organic acids or other iron chelators. Exogenous deferoxamine stimulated growth in extreme iron-limitation, while neither organic acids nor quartersaturated transferrins were stimulatory. These results suggest two iron uptake mechanisms, one dependent upon exogenous hydroxamate, the other hydroxamate-independent.

PMID:
3325632
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center